Ministers have been handing in their resignations, including chancellor Rishi Sunak and care minister Sajid Javid, leading to some shocked financial services professionals taking to Twitter.
Andrew Murrison MP has also announced on Twitter that he has resigned as a trade envoy.
Javid has been secretary of state for health and social care since June 2021; Sunak has been chancellor since 2020.
Consultant Roger Edwards said: "I go for a quick bath and get out to find Sunak and Javid have resigned."
Martin Bamford of Informed Choice, tweeted a photo of himself outside Downing Street, and said: "Hold tight y’all. I’ve got this."
Former Tory councillor and financial consultant Jonathan Purle joked: "Can you put me in charge of financial regulation, Martin?"
Alistair Cunningham, financial planning director at Wingate Financial Planning, said: "The problem with resigning in protest in the current government is it makes people think that your line has just been crossed by the current scandal, and not everything that preceded it.
"Suspect that's why so many still hold on."
Both Sunak and Javid are understood to have resigned after having no confidence in Prime Minister Boris Johnson to lead the country, following questions about Johnson's role in appointing MP Chris Pincher, who is facing sexual misconduct allegations, as deputy chief whip earlier this year.
It is unknown how many more MPs have been putting in their resignation; it is clear there will have to be an urgent response from the Conservative Party over the coming days.